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March 2022

Clinical Update: 

ASCO Guidelines for Germline Testing in 
Ovarian Cancer


The American Society of Clinical Oncology (ASCO) Guidelines for Ovarian Cancer focus on the screening, diagnosis, staging, treatment, and management considering individual risk assessment.

These updated guidelines include criteria for further genetic risk evaluation using a hereditary cancer panel for hereditary cancer syndromes:

·  All women diagnosed with ovarian cancer should be offered germline testing for BRCA1, BRCA2, and other ovarian cancer susceptibility genes, irrespective of their clinical features or family cancer history.

Germline testing should be ordered in appropriate individuals where it will impact the treatment, clinical trial options and risk management. The recommended panels should contain BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, MLH1, MSH2, MSH6, PMS2, and PALB2.

Genetics Institute of America’s GIAnomics™ Hereditary Cancer Panel includes all the recommended predisposition genes for Ovarian Cancer. GIA is committed to exceeding the standards put forth by prestigious organizations, like ASCO, and ensuring that the panels we offer support your medical needs and your patient’s health and safety.


Enroll your Practice in GH-101!

Genetics Institute of America is actively recruiting practices to join our study, GH-101! The objective of this study is to take an integrative approach to the fields of pharmacogenomics, cancer genomics, mRNA microarrays and nutrigenomics by identifying DNA and RNA variants in persons with chronic disease. We are looking for Physicians and Physician Groups that currently treat patients with a chronic disease including: cancer, cardiac conditions, diabetes, kidney disease, PTSD. Getting your practice involved is easy and not only gets patients the individualized health information they need but allows your practice to be on the cutting edge of genetic research. Click "Enroll Now" for more information about this study and enrolling your practice.


Have you Seen This?: 

Secondary Prevention of Non-BRCA Hereditary Cancer


Secondary prevention strategies specific to patient genotype will individualize treatment plans, enhance patient safety, and increase chance of survival.

It's All in the Genes:

Hereditary Cancer Genes Linked to Endometrial Cancer Development


The risk of hereditary endometrial cancer increases almost 2-fold with the presence of a pathogenic variant in a mismatch repair gene.

Changing Corporate Culture:

Ride 4 Orphans

Love for Orphans Across the World

Genetics Institute of America believes that it is our responsibility to care for the community we are a part of, and that corporate culture can do more to play a greater role in community solutions.


Thank you for the trust and confidence you have placed in our team here at the Genetics Institute of America. This monthly newsletter is our primary method of communicating to you important information about our testing and assays, general information about the Genetics Institute, as well as information impacting patient care and safety. If you would like to have another person in your practice receive these updates, please forward this to them so that they can subscribe.


Ana Perez-Miranda, PhD, MDxT (AAB), MB (ASCP)

Laboratory Manager and Molecular Diagnostics Supervisor

Genetics Institute of America


GIA Lab News is an educational service of Genetics Institute of America.

Genetics Institute of America is a national laboratory dedicated to heightening the awareness of early intervention and genetic screening to promote the longevity and quality of life outcomes. Our determination and research allow us to provide next generation DNA sequencing to deliver customized testing for identified genetic related cancers and other diseases.

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